MOTS-c 10mg – Mitochondrial-Derived Research Peptide

MOTS-c 10mg is a high-purity mitochondrial-derived research peptide supplied as white to off-white lyophilized powder in a sterile multidose vial. With a stated purity of ≥99%, this research-grade material is intended exclusively for qualified laboratory, biochemical, and scientific research.

MOTS-c is a 16-amino-acid peptide associated with the mitochondrial 12S rRNA region and has become an important subject within research involving mitochondrial biology, metabolic signaling, cellular energy regulation, and mitochondrial–nuclear communication. Current research literature and Canadian research-product catalogues describe MOTS-c in connection with AMPK-related signaling and cellular responses to metabolic stress.

Product Specifications

• Product: MOTS-c
• Strength: 10mg
• Purity: ≥99%
• Format: Multidose Vial
• Grade: Research Grade
• Appearance: White to off-white lyophilized powder
• Storage: 2°C–8°C
• Protection: Protect from light and moisture

The defined MOTS-c 10mg formulation provides researchers with a consistent research material for controlled investigations involving mitochondrial and metabolic pathways.

What Is MOTS-c?

MOTS-c stands for Mitochondrial Open Reading Frame of the 12S rRNA-c. Unlike conventional peptides encoded by nuclear DNA, MOTS-c is associated with a coding region within mitochondrial DNA, making it a distinctive subject in mitochondrial peptide research.

The peptide is composed of 16 amino acids and has been investigated as part of the emerging field of mitochondria-derived peptides. Research interest in MOTS-c centres on how mitochondrial status may interact with cellular metabolic signaling and broader cellular responses.

This mitochondrial origin is one of the characteristics that distinguishes MOTS-c from many other research peptides and makes it particularly relevant to studies examining communication between mitochondrial and nuclear processes.

MOTS-c Research Applications

The MOTS-c research peptide may be relevant to laboratory investigations involving several areas of molecular and cellular biology.

Mitochondrial Biology

MOTS-c is studied within mitochondrial biology as researchers investigate how mitochondria participate in cellular signaling beyond their established role in energy production.

Cellular Metabolism

Research involving MOTS-c examines metabolic signaling and cellular responses associated with energy balance and metabolic stress.

AMPK-Related Signaling

AMP-activated protein kinase (AMPK) is an important cellular energy-sensing pathway. MOTS-c has been investigated in relation to AMPK-associated signaling, making it relevant to controlled laboratory studies of cellular energy regulation.

Metabolic Homeostasis

Researchers may investigate MOTS-c in experimental models examining metabolic homeostasis and cellular responses to changing energy conditions.

Mitochondrial–Nuclear Communication

One area of particular interest is mitochondrial–nuclear communication. MOTS-c research contributes to investigation of how mitochondrial-derived signaling molecules may influence processes involving the nucleus and cellular metabolism.

Exercise Physiology Research

MOTS-c is also studied in experimental exercise-physiology models. These investigations can examine molecular and cellular responses associated with physical stress and energy metabolism.

Aging and Longevity Research

Mitochondrial function and metabolic regulation are important areas of aging biology. MOTS-c is consequently investigated in preclinical research exploring cellular changes associated with aging and metabolic stress.

These applications represent areas of scientific investigation, not established therapeutic or performance benefits in humans.

MOTS-c and Mitochondrial-Derived Peptide Research

MOTS-c is notable because of its mitochondrial genomic origin. Research into mitochondrial-derived peptides has expanded interest in the possibility that mitochondria may encode signaling molecules with functions extending beyond traditional mitochondrial biology.

MOTS-c therefore provides researchers with a useful model for investigating relationships between mitochondrial activity, cellular metabolism, stress responses, and intracellular signaling.

Published research has identified MOTS-c as a mitochondrial-derived peptide and investigated its relationship with metabolic regulation. Researchers should evaluate individual studies according to their experimental model, methodology, and limitations rather than treating preclinical observations as established clinical outcomes.

Research-Grade MOTS-c 10mg

This MOTS-c 10mg research compound is supplied at a stated purity of ≥99% and presented as white to off-white lyophilized powder.

The product is packaged in a sterile multidose vial and is intended for laboratory research where consistency and defined product specifications are important.

Researchers conducting analytical or experimental work should review the applicable batch documentation and Certificate of Analysis where available. Batch-specific analytical information is particularly important when experimental reproducibility depends on confirmed peptide identity and purity.

Storage

Store MOTS-c 10mg under refrigerated conditions at 2°C–8°C.

Protect the sealed product from:

• Direct light
• Moisture
• Excessive heat
• Uncontrolled environmental conditions

Researchers should maintain appropriate laboratory storage procedures and follow their institution’s requirements for research materials.

MOTS-c Research Peptide in Canada

BioMatrix Compounds provides MOTS-c 10mg strictly as a research-use material.

Canadian customers and research institutions should independently determine the requirements applicable to their intended research activities. Health Canada currently lists MOTS-C among examples of unauthorized injectable peptide drugs and warns that unauthorized injectable peptides have not been assessed for safety, efficacy, and quality by Health Canada.

For Canadian regulatory information, researchers should review the official Health Canada guidance on unauthorized injectable peptide products.

Scientific Research Resources

Researchers interested in the scientific background of MOTS-c can consult peer-reviewed literature covering mitochondrial-derived peptides, metabolic signaling, and mitochondrial biology.

For an authoritative scientific reference, see the PubMed research literature on MOTS-c and mitochondrial-derived peptides.

Related Research Compounds

Researchers studying metabolic and cellular signaling may also explore other BioMatrix Compounds research materials.

For example, CJC-1295 without DAC 10mg provides a different research model centred on GHRH-related and endocrine signaling. Comparing research compounds from different biological pathways can be useful when designing broader laboratory investigations into cellular signaling and metabolic physiology.

The KPV 10mg research peptide is another related catalog item for researchers investigating peptide biology and cellular signaling, although its research field differs from the mitochondrial focus of MOTS-c.

Research Use Only Disclaimer

For Research Use Only.

This product is intended exclusively for laboratory research purposes. Not for human or veterinary use.

It is not intended for consumption, diagnosis, treatment, cure, or prevention of any disease or medical condition.

Nothing on this product page should be interpreted as medical advice, therapeutic guidance, dosage guidance, performance-enhancement guidance, or a recommendation for personal use.

Researchers are responsible for determining the suitability of this material for their intended laboratory application and for complying with all applicable federal, provincial, institutional, and laboratory requirements.

MOTS-c 10mg | ≥99% Purity | Mitochondrial-Derived Research Peptide | Research Grade